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CSF phenylacetic acid and hostility in paranoid schizophrenia
K F Faull1, R J King, J D Barchas
1Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, CA 94305.
Psychiatry Research
|November 1, 1989
Abstract:
Lumbar cerebrospinal fluid concentrations of phenylacetic acid were significantly elevated in paranoid vs. nonparanoid schizophrenics. Further, phenylacetic acid concentrations were correlated with hostility. These results are consistent with the hypothesis that phenylethylamine, the proposed precursor of phenylacetic acid, plays a role in schizophrenia.