Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Determination of Crystal Structures01:29

Determination of Crystal Structures

111
In the late 1800s, the revelation that light extended beyond visible wavelengths led to the discovery of X-rays by Wilhelm Roentgen. Recognized as high-energy electromagnetic radiation with short wavelengths, X-rays prompted exploration into their interaction with crystals. Max von Laue proposed in 1912 that the periodic arrangement of atoms, ions, or molecules in crystals would cause them to diffract X-rays, a hypothesis confirmed through experiments with copper sulfate and zinc sulfide...
111
Mass Analyzers: Common Types01:19

Mass Analyzers: Common Types

1.9K
The quadrupole mass analyzer consists of four cylindrical metal rods arranged in a diamond carrying a DC voltage and a radio-frequency AC voltage. The motion of ions through the quadrupole depends on the field strength, causing only ions of a certain m/z to resonate successfully and strike the detector at a given field strength. Though the transmission rate for these analyzers is high, the exact elemental composition of the sample is not determined because of low resolution; however, they are...
1.9K
X-ray Imaging01:24

X-ray Imaging

11.1K
German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
11.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neurobehavioral Profiles in Young Steroid-Naive Boys With Duchenne Muscular Dystrophy: A Baseline Data Analysis From the FOR-DMD Trial.

Neurology·2026
Same author

Pretargeted <sup>177</sup>Lu/<sup>225</sup>Ac combination therapy of colorectal cancer.

Theranostics·2026
Same author

Characterization and Calibration of the iQID Digital Autoradiography System for Direct Quantitative Imaging of Beta-Emitters in Tissue Samples.

bioRxiv : the preprint server for biology·2026
Same author

Spatial uniformity and resolution in inkjet-printed <sup>241</sup>Am phantoms imaged by digital autoradiography.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2025
Same author

Comparison of targeting two antigens (GPA33 versus HER2) for <sup>225</sup>Ac-pretargeted alpha-radioimmunotherapy of colorectal cancer.

Theranostics·2025
Same author

Analytical methods for system matrix calculation and spatial resolution evaluation of DC-SPECT system.

Physics in medicine and biology·2025

Related Experiment Video

Updated: Apr 7, 2026

Photoelectron Imaging of Anions Illustrated by 310 Nm Detachment of F&#8722;
06:53

Photoelectron Imaging of Anions Illustrated by 310 Nm Detachment of F−

Published on: July 27, 2018

9.3K

The iQID camera: An ionizing-radiation quantum imaging detector.

Brian W Miller1, Stephanie J Gregory2, Erin S Fuller2

  • 1Pacific Northwest National Laboratory, Richland, WA 99352, USA ; College of Optical Sciences, The University of Arizona, Tucson, AZ 85719, USA.

Nuclear Instruments & Methods in Physics Research. Section A, Accelerators, Spectrometers, Detectors and Associated Equipment
|July 14, 2015
PubMed
Summary

A novel ionizing-radiation Quantum Imaging Detector (iQID) demonstrates broad applicability for various particle types. This versatile detector offers real-time imaging with high spatial resolution for diverse scientific applications.

Keywords:
BazookaSPECTCharged particle imaging detectorsDigital autoradiographyIonizing radiation

More Related Videos

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera
06:28

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera

Published on: January 30, 2020

13.4K
Resonance Fluorescence of an InGaAs Quantum Dot in a Planar Cavity Using Orthogonal Excitation and Detection
12:57

Resonance Fluorescence of an InGaAs Quantum Dot in a Planar Cavity Using Orthogonal Excitation and Detection

Published on: October 13, 2017

9.7K

Related Experiment Videos

Last Updated: Apr 7, 2026

Photoelectron Imaging of Anions Illustrated by 310 Nm Detachment of F&#8722;
06:53

Photoelectron Imaging of Anions Illustrated by 310 Nm Detachment of F−

Published on: July 27, 2018

9.3K
Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera
06:28

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera

Published on: January 30, 2020

13.4K
Resonance Fluorescence of an InGaAs Quantum Dot in a Planar Cavity Using Orthogonal Excitation and Detection
12:57

Resonance Fluorescence of an InGaAs Quantum Dot in a Planar Cavity Using Orthogonal Excitation and Detection

Published on: October 13, 2017

9.7K

Area of Science:

  • Nuclear physics
  • Medical imaging
  • Radiation detection

Background:

  • The ionizing-radiation Quantum Imaging Detector (iQID) originated as BazookaSPECT, a high-resolution gamma-ray imager for single-photon emission computed tomography (SPECT).
  • Recent investigations have expanded the detector's scope to include alpha, neutron, beta, and fission fragment particles.

Purpose of the Study:

  • To characterize the response of the iQID to a wide spectrum of ionizing radiation.
  • To evaluate its potential for real-time imaging across different particle types.
  • To highlight its utility in advanced applications like digital autoradiography.

Main Methods:

  • The iQID camera couples a scintillator with an image intensifier to optically amplify scintillation light from particle interactions.
  • Scintillation events are re-imaged onto a CCD/CMOS sensor for analysis.
  • Real-time event-by-event estimation of particle location and energy uses image analysis algorithms on graphics processing hardware.

Main Results:

  • The iQID exhibits confirmed response to gamma rays, alpha, neutron, beta, and fission fragment particles.
  • Key features include portability, large active areas, high detection efficiency for charged particles, and spatial resolution in the tens of microns.
  • The system provides modest energy resolution sufficient for particle discrimination, complemented by spatial event feature analysis.

Conclusions:

  • The iQID is a versatile, portable detector capable of imaging diverse ionizing radiation with high spatial resolution.
  • Its ability to perform real-time, single-particle digital autoradiography represents a significant advancement.
  • The detector holds potential for broad applications in nuclear physics, medical imaging, and radiation detection.