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Autologous Fat Grafting Improves Facial Nerve Function.

Marco Klinger1, Andrea Lisa1, Fabio Caviggioli2

  • 1Reconstructive and Aesthetic Plastic Surgery School, Department of Medical Biotechnology and Translational Medicine (BIOMETRA), University of Milan, Plastic Surgery Unit, Humanitas Research Hospital, Rozzano, 20089 Milan, Italy.

Case Reports in Surgery
|July 14, 2015
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Summary

Autologous fat grafting effectively treated a painful scar causing mouth movement impairment. This regenerative therapy improved scar retraction, reduced pain, and restored facial functions within a year.

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Area of Science:

  • Regenerative Medicine
  • Plastic Surgery
  • Neurology

Background:

  • Traumatic injuries can result in retractile scars, leading to functional impairments such as motor deficits.
  • Scar tissue can entrap peripheral nerves, potentially causing loss of function and pain.
  • Limited therapeutic options exist for managing complex scar retraction and associated nerve dysfunction.

Purpose of the Study:

  • To evaluate the efficacy of autologous fat grafting in treating a retractile scar with associated motor impairment.
  • To assess the impact of fat grafting on scar tissue characteristics and peripheral nerve function.
  • To explore the regenerative potential of autologous fat grafting in scar management.

Main Methods:

  • A case study of a 45-year-old male with a nasolabial scar causing partial mouth movement impairment.
  • Treatment involved autologous fat grafting using Coleman's technique.
  • Clinical assessments were conducted at multiple intervals post-procedure (5 days, 14 days, 1, 3, and 6 months), with a second procedure at 6 months.

Main Results:

  • Progressive release of scar retraction was observed.
  • Significant improvement in pain symptoms was noted.
  • Total restoration of mimic movements was achieved within one year of follow-up.

Conclusions:

  • Autologous fat grafting demonstrates a significant regenerative effect on scar tissue.
  • The procedure offers a potential therapeutic approach for scar-related motor impairments.
  • Fat grafting may positively influence peripheral nerve activity, possibly by alleviating entrapment within scar tissue.