Related Experiment Videos
Changing trends in acute renal failure in third-world countries--Chandigarh study
K S Chugh1, V Sakhuja, H S Malhotra
1Department of Nephrology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
The Quarterly Journal of Medicine
|December 1, 1989
Summary
The causes of acute renal failure in India are shifting, with fewer cases from diarrheal diseases and obstetrical complications. However, surgical causes, particularly obstructive uropathy, are increasing, highlighting evolving health challenges.
Area of Science:
- Nephrology
- Public Health
- Epidemiology
Background:
- Acute renal failure (ARF) patterns differ globally, with developing nations facing unique challenges.
- Understanding ARF trends is crucial for targeted public health interventions in resource-limited settings.
Purpose of the Study:
- To analyze the changing patterns of acute renal failure (ARF) causes in a North Indian tertiary care center over two decades (1965-1986).
- To compare these trends with those observed in developed countries.
Main Methods:
- Retrospective analysis of 1862 patients with ARF requiring dialysis between 1965 and 1986.
- Categorization of ARF causes into medical, obstetrical, and surgical conditions.
- Comparison of etiological distribution across different time periods (1965-1974 vs. 1981-1986).
Main Results:
- Medical causes decreased from 60% to 48%, with diarrheal diseases dropping significantly (23% to 10%).
- Obstetrical ARF declined from 22% to 9%, attributed to reduced septic abortions and postpartum hemorrhage.
- Surgical ARF increased from 11% to 31%, primarily due to obstructive uropathy.
Conclusions:
- While ARF patterns in India show some convergence with developed nations, significant differences persist.
- The rise in surgical ARF, especially obstructive uropathy, necessitates focused preventive strategies.
- Continued epidemiological surveillance is vital for adapting healthcare strategies to evolving ARF etiologies in developing countries.