Non-Systemic Vasculitic Neuropathy: An Enigmatic Clinical Entity
Sandeep Singh Lubana1, Navdeep Singh1, Susan Sanelli-Russo2
1Department of Internal Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, Queens, NY, USA.
The American Journal of Case Reports
|July 14, 2015
Summary
Non-systemic vasculitic peripheral neuropathy, a rare condition, can be missed in diabetic patients. Combining skin biopsy with lower limb angiography may avoid invasive nerve biopsies.
Area of Science:
- Neurology
- Vascular Medicine
- Dermatology
Background:
- Non-systemic vasculitic peripheral neuropathy involves inflammation of small blood vessels supplying nerves.
- This condition can lead to nerve ischemia and significant patient morbidity.
Observation:
- A 63-year-old woman with uncontrolled diabetes presented with severe lower extremity pain and foot drop.
- Initial treatments and diagnostics were insufficient; skin biopsy revealed vasculitis.
Findings:
- The patient was diagnosed with non-systemic vasculitic peripheral neuropathy.
- Electromyography confirmed peripheral neuropathy, necessitating further investigation.
Implications:
- Early diagnosis is crucial, as delays can increase patient morbidity.
- Non-invasive imaging like magnetic resonance angiography combined with skin biopsy may obviate the need for nerve biopsy.
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