Related Experiment Video For Bladder exstrophy–epispadias complex
Updated: Apr 7, 2026

An Orthotopic Bladder Cancer Model for Gene Delivery Studies
Published on: December 1, 2013
Squamous cell carcinoma at bladder exstrophy site after early cystectomy
Giulia Ippolito Lane1, Mary Kwaan2, Jane Lewis3
1Department of Urology, University of Minnesota, Mayo Memorial Building, 420 Delaware St. SE MMC 394, Minneapolis, MN, 55455, USA. ippol007@umn.edu.
Abstract:
Patients with bladder exstrophy-epispadias complex (BEEC) are at risk for bladder cancer, usually this presents as adenocarcinoma (Smeulders "BJU Int" 87:623-628, 2001). Squamous cell carcinoma (SCC) is rare, with only 13 documented case reports. This is a case of SCC in a 78-year-old man with BEEC who underwent cystectomy and ureterosigmoidostomy in childhood.
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