Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prediction of Posterior Communicating Artery Aneurysm Rupture Risk: A Multivariate Analysis of Aneurysm and Surrounding Arterial Morphological Factors.

Journal of clinical medicine·2026
Same author

Synthesis of coronary 4D CT Image by denoising diffusion probabilistic model.

Computer methods and programs in biomedicine·2026
Same author

Effect of a Localized Oxygen-Releasing Hydrogel Sheet on Early-Stage Infarct Evolution in a Rat Photothrombotic Stroke Model: A Preliminary Study.

Gels (Basel, Switzerland)·2026
Same author

Influence of Fetal-Type Posterior Cerebral Artery on Morphological Characteristics and Rupture Risk of Posterior Communicating Artery Aneurysms: A Radiomics Approach.

Journal of clinical medicine·2025
Same author

Capillary flow-driven immunoassay platform for COVID-19 antigen diagnostics.

Analytica chimica acta·2023
Same author

Correct Closure of the Left Atrial Appendage Reduces Stagnant Blood Flow and the Risk of Thrombus Formation: A Proof-of-Concept Experimental Study Using 4D Flow Magnetic Resonance Imaging.

Korean journal of radiology·2023

Related Experiment Video

Updated: Apr 7, 2026

Using Adhesive Patterning to Construct 3D Paper Microfluidic Devices
07:53

Using Adhesive Patterning to Construct 3D Paper Microfluidic Devices

Published on: April 1, 2016

8.1K

Facile and precise flow control for a paper-based microfluidic device through varying paper permeability.

Ilhoon Jang1, Simon Song

  • 1Dept. of Mechanical Convergence Engineering, Hanyang University, 222 Wangsimni-ro, Seongdong-gu, Seoul, 133-791, South Korea. simonsong@hanyang.ac.kr.

Lab on a Chip
|July 15, 2015
PubMed
Summary

Researchers developed a simple method to control fluid flow in paper-based microfluidic devices by adjusting wax patterns. This technique precisely manages flow rates and mixing ratios for low-cost sensor applications.

More Related Videos

Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays
11:33

Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays

Published on: March 9, 2017

16.6K
Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

22.0K

Related Experiment Videos

Last Updated: Apr 7, 2026

Using Adhesive Patterning to Construct 3D Paper Microfluidic Devices
07:53

Using Adhesive Patterning to Construct 3D Paper Microfluidic Devices

Published on: April 1, 2016

8.1K
Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays
11:33

Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays

Published on: March 9, 2017

16.6K
Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
18:11

Microfluidic Chips Controlled with Elastomeric Microvalve Arrays

Published on: October 1, 2007

22.0K

Area of Science:

  • Microfluidics
  • Analytical Chemistry
  • Materials Science

Background:

  • Paper-based microfluidic devices leverage capillary action for flow, enabling low-cost, portable diagnostics.
  • Precise control over fluid flow rates remains a challenge for complex functionalities in these devices.

Purpose of the Study:

  • To propose and validate a facile method for controlling fluid flow rates in paper-based microfluidic devices.
  • To demonstrate the application of this flow control method in a paper-based micromixer.

Main Methods:

  • Utilized wax printing to create variable permeability patterns on chromatography paper.
  • Investigated the relationship between wax pattern brightness/length and fluid flow rate.
  • Developed and tested a paper-based micromixer using the developed flow control technique.

Main Results:

  • Demonstrated precise control of flow rates by adjusting wax pattern brightness (inversely proportional to wax amount) and length.
  • Achieved accurate control over the mixing ratios of two dye flows in a paper-based micromixer.
  • Experimental mixing ratios closely matched predicted values.

Conclusions:

  • Wax printing offers a simple yet effective method for precise flow rate control in paper-based microfluidic devices.
  • This technique facilitates the development of sophisticated paper-based analytical devices with customizable functionalities.
  • The developed micromixer showcases the potential for accurate fluid manipulation in low-cost, paper-based platforms.