[Myocardial infarction of rare etiology in a young adult]
Gábor Zoltán Nagy1, Gábor Gerges, Kálmán Csapó
1I. Belgyógyászat, Kardiológiai Osztály, Borsod-Abaúj-Zemplén Megyei Kórház és Egyetemi Oktatókórház Miskolc, Szentpéteri kapu 72-76., 3526.
Insights
Chest pain in young adults is rare for acute coronary syndrome, often leading to misdiagnosis. This case highlights left main coronary artery occlusion as a critical, yet challenging, diagnosis in this demographic.
Area of Science:
- Cardiology
- Emergency Medicine
- Pathology
Background:
- Chest pain is a common symptom in emergency departments, but acute coronary syndrome (ACS) is rare in patients under 35.
- Diagnostic errors can occur due to the low prevalence of ACS in younger populations.
Observation:
- A 19-year-old female presented with sudden chest pain and malaise, showing ST-segment elevation on ECG.
- Initial evaluation for aortic dissection via CT scan was negative.
- Coronary angiography revealed total occlusion of the left main coronary artery.
Findings:
- Percutaneous coronary intervention successfully opened the occluded artery.
- Despite revascularization, the patient died due to asystole.
- Autopsy confirmed thrombotic embolization of the left main artery, leading to extensive myocardial necrosis.
Implications:
- Left coronary artery occlusion presents a diagnostic challenge in young patients, mimicking conditions like aortic dissection or pulmonary embolism.
- This case underscores the importance of considering rare cardiac causes of chest pain in all age groups.
- The source of the thrombotic embolization remained unidentified, warranting further investigation into potential underlying causes.
Abstract:
Chest pain is not uncommon among young patients below the age of 35 years, however, it is rarely caused by acute coronary syndrome. The rarity of coronary artery occlusion in this population can easily lead to diagnostic mistakes. The authors present the case history of a 19-year-old young female, who was admitted to the emergency department of a local hospital due to the sudden onset of chest pain and malaise. ST-segment elevation was seen on the electrocardiogram raising the possibility of aortic dissection, therefore, emergency thoracic computed tomographic scan was performed. This proved to be negative and the patient was transferred to the coronary care unit. Urgent coronarography was carried out, which revealed the total occlusion of the left main coronary artery. The occluded artery was successfully opened with percutaneous coronary intervention, but despite revascularisation the patient died on the second postoperative day due to asystole. Autopsy revealed thrombotic embolization of the left main artery with consequent extensive haemorrhagic necrosis, involving almost the whole left ventricle. The source of embolization was not found. The authors note that left coronary artery occlusion in young patients can be a diagnostic challenge, because symptoms can be mistaken with aortic dissection or pulmonary embolism.
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