Related Experiment Video
Updated: Apr 7, 2026

Evaluating Virulence and Pathogenesis of Aeromonas Infection in a Caenorhabditis elegans Model
Published on: December 20, 2018
Necrotizing Urethritis due to Aerococcus urinae
Abdulrahman A Babaeer1, Claudia Nader2, Vito Iacoviello2
1Urology Department, St. Elizabeth Medical Center, Brighton, MA 02135, USA.
Abstract:
A 49-year-old male presented to the emergency with hematuria and pain in the shaft of the penis for one day. The patient was found to be in a state of shock. The shaft of the penis and the scrotum were swollen and tender. No skin necrosis was observed and no crepitus was palpable. Serum white count (WBC) was 29.5 × 10(3)/μL. A CT scan showed gas in the corpus spongiosum. Antibiotics were started with IV metronidazole, vancomycin, and piperacillin/tazobactam. Metronidazole was then replaced by clindamycin. Exploration was performed but no necrotic tissue was identified. Cystourethroscopy revealed dusky looking urethra. A suprapubic tube and a urethral catheter were placed in the bladder. WBC trended down to 13.9 × 10(3)/μL on the fourth postoperative day. Urine culture grew Aerococcus urinae and blood cultures grew Alpha Hemolytic Streptococcus. On the sixth day, the patient was feeling worse and WBC increased. MRI revealed absent blood flow to the corpus spongiosum. Urethroscopy revealed necrosis of the urethra. Urethrectomy was performed via perineal approach. The patient immediately improved. The patient was discharged on the sixth postoperative day to continue ampicillin/sulbactam IV every 6 hours for a total of 4 weeks from the day of urethrectomy.
Related Concept Videos
Microbiota of the Urogenital Tract
Urinary Tract Infection II: Pathophysiology
Acute Pyelonephritis I: Introduction
Urinary Tract Infection I: Introduction
Acute Pyelonephritis II: Diagnostic Studies and Management
Atypical Pneumonia

