Related Experiment Video
Updated: Apr 7, 2026
06:15
Evaluating Virulence and Pathogenesis of Aeromonas Infection in a Caenorhabditis elegans Model
Published on: December 20, 2018
8.1K
Necrotizing Urethritis due to Aerococcus urinae.
Abdulrahman A Babaeer1, Claudia Nader2, Vito Iacoviello2
1Urology Department, St. Elizabeth Medical Center, Brighton, MA 02135, USA.
Case Reports in Urology
|July 15, 2015
Summary
A rare case of Fournier
Area of Science:
- Urology
- Infectious Disease
Background:
- Fournier's gangrene is a severe necrotizing infection of the genitalia.
- Early diagnosis and aggressive management are crucial for patient survival.
Purpose of the Study:
- To report a unique case of Fournier's gangrene involving the corpus spongiosum and urethra.
- To highlight the diagnostic challenges and treatment outcomes in such cases.
Main Methods:
- Case presentation of a 49-year-old male with shock, penile, and scrotal swelling.
- Diagnostic imaging including CT and MRI, cystourethroscopy, and laboratory tests.
- Multimodal treatment including broad-spectrum antibiotics, surgical exploration, urethroscopy, and urethrectomy.
Main Results:
- Initial CT showed gas in the corpus spongiosum; MRI revealed absent blood flow to the corpus spongiosum.
- Urethroscopy initially showed a dusky urethra, later revealing necrosis.
- Urethrectomy led to immediate patient improvement and discharge on IV antibiotics.
Conclusions:
- Fournier's gangrene can present with unusual findings like corpus spongiosum gas and progress to urethral necrosis.
- Aggressive surgical intervention, including urethrectomy, may be necessary for limb salvage and recovery.
- Prompt diagnosis and tailored antibiotic therapy are vital for managing this critical condition.
Related Concept Videos
01:28Microbiota of the Urogenital Tract
43
The human urogenital system, once thought to be sterile in healthy individuals, is now recognized as a complex microbial habitat. Advancements in molecular sequencing techniques have revealed that even in healthy adults, the kidneys and bladder harbor microbial populations similar to those found in the distal urethra, albeit in much lower abundance. These resident microorganisms, while generally innocuous, can become opportunistic pathogens under conditions that alter the urogenital...
43
01:25Urinary Tract Infection II: Pathophysiology
1.2K
The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
1.2K
01:27Acute Pyelonephritis I: Introduction
1.2K
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
1.2K
01:26Urinary Tract Infection I: Introduction
1.1K
Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
1.1K
01:28Acute Pyelonephritis II: Diagnostic Studies and Management
668
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
668
01:14Atypical Pneumonia
49
Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease...
49