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Related Experiment Video

Updated: Apr 7, 2026

Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides
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Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides

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Fulleropeptide esters as potential self-assembled antioxidants.

Mira S Bjelaković1, Tatjana J Kop1, Jelena Đorđević2

  • 1Institute of Chemistry, Technology and Metallurgy, Center for Chemistry, University of Belgrade, Njegoševa 12, P.O. Box 473, 11001 Belgrade, Serbia.

Beilstein Journal of Nanotechnology
|July 15, 2015
PubMed
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Amphiphilic fullerene derivatives show significant antioxidant capacity, outperforming vitamin C. These bionanomaterials self-assemble into ordered structures, with size and shape influenced by concentration and side chain.

Area of Science:

  • Nanomaterials Science
  • Biochemistry
  • Physical Chemistry

Background:

  • Fullerene derivatives are explored for bionanomaterial applications.
  • Understanding their antioxidant properties and self-assembly is crucial.

Purpose of the Study:

  • To investigate the antioxidant capacity of amphiphilic fullerene derivatives.
  • To explore their self-assembly into ordered nanostructures.

Main Methods:

  • Cyclic voltammetry (CV) for electrochemical analysis.
  • Scanning electron microscopy (SEM) for morphology.
  • Ferrous ion oxidation-xylenol orange (FOX) assay for antioxidant capacity.

Main Results:

  • Amphiphilic fullerene derivatives exhibit high antioxidant capacity, exceeding pristine C60 and vitamin C.
Keywords:
FOX assayantioxidant activitycyclic voltammetryfulleropeptide estersscanning electron microscopy

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Last Updated: Apr 7, 2026

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  • Peroxide quenching was 2-fold higher than C60 and 5-12-fold higher than vitamin C.
  • Spontaneous self-assembly into ordered structures was observed, dependent on concentration and side chain.

    • Conclusions:

    • Amphiphilic fullerene derivatives are promising bionanomaterials with potent antioxidant properties.
    • Their ability to form ordered structures offers potential for advanced material design.
    • Concentration and side chain structure are key factors in controlling nanostructure formation.