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Published on: December 23, 2022
Percutaneous Closure of Perimembranous Ventricular Septal Defect with Modified Double-disk Occluder: What Is the
Yuan Bai1, Jing Liu1, Yong-Wen Qin1
1Department of Cardiology, Changhai Hospital, The Second Military Medical University, Shanghai, China.
Objective:
Percutaneous closure of perimembranous ventricular septal defect is one of the greatest challenges in interventional cardiology. The long-term follow-up data are still limited. This report presents our experience in percutaneous closure of perimembranous ventricular septal defect with modified double-disk occluder.
Design:
The study is a retrospective analysis of cases from the Changhai Hospital clinic database.
Setting:
We reviewed the clinic database from December 2001 to December 2005.
Patients:
We included 117 patients who underwent percutaneous closure of perimembranous ventricular septal defects.
Outcome Measures:
Procedural data and complications were assessed by an expert panel of cardiologists.
Results:
Device implantation was successfully accomplished in 113 of a total 117 patients (96.6%). The mean age was 31.1 ± 12.5 years (range 2-56 years). The patients were followed for a period of 86-134 months. The diameter of defect was 2-15 mm (mean 4.9 ± 2.9 mm). The ventricular septal defect rim below the aortic valve was 1-5 mm. The mean diameter of device used was 6.9 ± 3.7 (range 4-24 mm). Four patients presented complete atrio-ventricular block within 1 week after the procedure and recovered within 3 weeks. No other patient encountered serious adverse events during the follow-up.
Conclusions:
Percutaneous closure of ventricular septal defect is safe and effective in most selected patients with modified double-disk occluder. Additional studies with larger cohorts and longer follow-up are needed to evaluate its safety.
