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Related Experiment Video

Updated: Apr 7, 2026

Laparoscopic Left Hemihepatectomy Combined with Caudate Lobe Resection

Laparoscopic Left Hemihepatectomy Combined with Caudate Lobe Resection

Published on: April 11, 2025

Intrahepatic cholangiocarcinoma: expert consensus statement.

Sharon M Weber¹, Dario Ribero², Eileen M O'Reilly³

¹Department of Surgery, University of Wisconsin, Madison, WI, USA.

HPB : the Official Journal of the International Hepato Pancreato Biliary Association

|July 15, 2015

Summary

Management of intrahepatic cholangiocarcinoma (ICC) requires a multidisciplinary approach. Surgical resection is key, with regional lymphadenectomy standard for resectable ICC. Adjuvant therapy and clinical trials are recommended for high-risk patients.

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Last Updated: Apr 7, 2026

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Intraoperative Strategy under Complex Vascular Adhesion for Laparoscopic Radical Resection of Bismuth-Corlette Type IIIb Perihilar Cholangiocarcinoma

Intraoperative Strategy under Complex Vascular Adhesion for Laparoscopic Radical Resection of Bismuth-Corlette Type IIIb Perihilar Cholangiocarcinoma

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Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb

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Published on: January 17, 2025

Area of Science:

Hepatobiliary Surgery
Surgical Oncology
Gastroenterology

Background:

Intrahepatic cholangiocarcinoma (ICC) management necessitates a coordinated, multidisciplinary strategy for optimal patient survival.
Current evidence on ICC treatment requires review to establish practice guidelines.

Purpose of the Study:

To review current evidence on intrahepatic cholangiocarcinoma (ICC) management.
To establish practice guidelines and consensus statements for ICC treatment.

Main Methods:

A consensus meeting of expert panellists sponsored by the American Hepato-Pancreato-Biliary Association (AHPBA).
Review of current evidence on ICC management.
Agreement on consensus statements regarding diagnosis, resectability, surgical therapy, and adjuvant treatment.

Main Results:

Biopsy is not necessary for suspected ICC planned for resection but required before systemic/locoregional therapies.
Cross-sectional imaging (CT/MRI) is best for assessing resectability; the role of PET is unclear.
Regional lymphadenectomy is a standard surgical therapy; diagnostic laparoscopy is recommended for high-risk patients.

Conclusions:

Surgical resection is the primary treatment for ICC, defined by complete disease removal with adequate liver remnant.
Extrahepatic disease, multiple/multicentric tumors, and extensive lymph node metastases are contraindications for resection.
Cisplatin plus gemcitabine is the standard first-line therapy for metastatic ICC; genomic analyses support targeted therapies.