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Related Concept Videos

Ostomy Care01:24

Ostomy Care

3.1K
Introduction
An ostomy is a surgical procedure that creates an artificial opening from the intestines to the outside of the body, allowing for the rerouting of effluent. This opening is known as a stoma. A stoma usually protrudes above the skin surface, appearing pink or red, moist, and round, and it lacks nerve sensations.
There are different types of ostomies, including colostomies, ileostomies, and urostomies:
3.1K
Drugs Affecting GI Tract Motility: Other Laxatives01:20

Drugs Affecting GI Tract Motility: Other Laxatives

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Laxatives are primarily used to alleviate constipation, a common gastrointestinal disorder characterized by infrequent bowel movements and difficulty passing stools. They work by various mechanisms to increase the volume or frequency of bowel movements. The primary modes of action of laxatives include increasing stool bulk, softening the stool, stimulating intestinal motility, and osmotically drawing water into the intestines.
Osmotic or saline laxatives, like magnesium hydroxide or milk of...
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Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents01:17

Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents

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Diarrhea, a condition marked by frequent loose or watery bowel movements, can be triggered by multiple factors such as viral or bacterial infections, food intolerances, anxiety, medications, and digestive disorders. Symptoms may include abdominal pain, bloating, nausea, and cramping. Severe or prolonged diarrhea can lead to complications like electrolyte imbalances, malnutrition, and dehydration if left untreated.
Opioids, widely used antidiarrheal agents, mitigate diarrhea by slowing down...
918
Peptic Ulcer Disease IV: Management01:26

Peptic Ulcer Disease IV: Management

663
Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
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Drugs Affecting GI Tract Motility: Adsorbents as Antidiarrheal Agents01:20

Drugs Affecting GI Tract Motility: Adsorbents as Antidiarrheal Agents

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Diarrhea is characterized by the occurrence of frequent, watery bowel movements. Various factors can trigger diarrhea, including viral or bacterial infections, foodborne illnesses, side effects from certain medications, and underlying digestive disorders. If not adequately managed, diarrhea can lead to complications such as dehydration, electrolyte imbalances, and nutrient deficiencies. Severe diarrhea can lead to significant weight loss, malnutrition, and weakened immune function.
Adsorbents...
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Related Experiment Video

Updated: Apr 7, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
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A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

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Medications and the Ostomate.

Richard Atkins1

  • 1Passavant Area Hospital, Jacksonville, Illinois, USA.

The Consultant Pharmacist : the Journal of the American Society of Consultant Pharmacists
|July 15, 2015
PubMed
Summary

Pharmacists must understand how ostomy surgery impacts medication absorption and effects. This review covers key pharmacokinetic and pharmacodynamic principles for ostomy patients, addressing common medication-related issues.

Area of Science:

  • Pharmacology
  • Gastroenterology
  • Patient Care

Background:

  • Over one million Americans have undergone ostomy surgery, with over 130,000 new procedures annually.
  • Ostomy patients present unique challenges regarding medication efficacy and safety.
  • Pharmacists require specialized knowledge to manage ostomates' drug therapy effectively.

Purpose of the Study:

  • To review the application of pharmacokinetic and pharmacodynamic principles in ostomy patient medication management.
  • To highlight critical considerations for pharmacists caring for individuals with ostomies.
  • To provide a foundation for optimizing drug therapy in this patient population.

Main Methods:

  • Review of basic pharmacokinetic principles (absorption, distribution, metabolism, excretion) in the context of ostomy.

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  • Review of basic pharmacodynamic principles (drug effects on the body) relevant to ostomy patients.
  • Discussion of specific clinical issues encountered in ostomy medication management.

    • Main Results:

    • Altered drug absorption can occur due to changes in gastrointestinal transit time and surface area post-ostomy.
    • Pharmacokinetic and pharmacodynamic principles must be adapted for ostomy patients to ensure therapeutic outcomes.
    • Common issues include challenges with controlled-release formulations, antibiotic-associated diarrhea, and potential for electrolyte imbalances.

    Conclusions:

    • Pharmacists play a vital role in optimizing medication use for ostomy patients.
    • Understanding drug disposition and effects in ostomates is crucial for preventing adverse events and ensuring treatment success.
    • Further research and education are needed to address the complexities of pharmacotherapy in individuals with ostomies.