[Pure squamous cell carcinoma and mixed transitional and squamous carcinoma of the bladder. A...

The histopathological features and clinical courses of 32 patients with pure squamous cell carcinomas of urinary bladder and 42 mixed squamous and transitional carcinomas were compared. The natural history of 2 patients populations was based on the staging of specimens on which first histological diagnosis was made and on the specific treatments adopted. No significant differences in behaviour between two histological types were observed, even though median survival of pure squamous forms was lower than that of mixed forms. Only radical treatments seemed to offer a better prognosis for mixed transitional and squamous forms with pT2 stage, whereas none of the patients with squamous carcinomas survived for two years regardless of stage and treatment performed. A common origin between the two histological types of tumour is supposed.