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Updated: Apr 7, 2026
Evaluation of Biomarkers in Glioma by Immunohistochemistry on Paraffin-Embedded 3D Glioma Neurosphere Cultures
Published on: January 9, 2019
Genetic Classification of Gliomas: Refining Histopathology
Michael B Foote1, Nickolas Papadopoulos1, Luis A Diaz1
1The Swim Across America Laboratory at Johns Hopkins, Baltimore, MD 21287, USA; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287, USA; The Ludwig Center for Cancer Genetics and Therapeutic at Johns Hopkins, Baltimore, MD 21287, USA.
Abstract:
Newly published studies validate prior reports that specific combinations of genetic alternations in IDH1/2, ATRX, TERT, TP53, and co-deletion of 1p/19q have the ability to reclassify gliomas into rational subsets, defining a glioma's biological and clinical behavior more accurately than stratifications based solely on histopathology.
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