Tremor and Klinefelter's Syndrome
Marcie L Rabin1, Shivam Om Mittal2, Bahman Jabbari3
1Atlantic Neuroscience Institute, Summit, NJ, USA.
Background:
Klinefelter's syndrome (KS) has been associated with tremor, but reports on tremor phenomenology and treatment are limited.
Case Reports:
Patient 1 is a 17-year-old male with a dystonic tremor treated with deep brain stimulation (DBS). Patient 2 is a 57-year-old male with a predominant left hand resting tremor and dystonic features.
Discussion:
Our cases suggest that the tremor in patients with KS may be dystonic in nature. Patient 1 is also the third reported case of successful treatment with DBS. These cases have implications for elucidating the underlying neurobiological mechanism of tremor and identifying treatment options.
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