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Updated: Apr 7, 2026

Heterotopic Auxiliary Rat Liver Transplantation With Flow-regulated Portal Vein Arterialization in Acute Hepatic Failure
Published on: September 13, 2014
Simplified technique for auxiliary orthotopic liver transplantation using a whole graft
Vinicius Rocha-Santos1, Lucas Souto Nacif1, Rafael Soares Pinheiro1
1Departamento de Gastroenterologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
Background:
Acute liver failure is associated with a high mortality rate and the main purposes of treatment are to prevent cerebral edema and infections, which often are responsible for patient death. The orthotopic liver transplantation is the gold standard treatment and improves the 1-year survival.
Aim:
To describe an alternative technique to auxiliary liver transplant on acute liver failure.
Method:
Was performed whole auxiliary liver transplantation as an alternative technique for a partial auxiliary liver transplantation using a whole liver graft from a child removing the native right liver performed a right hepatectomy. The patient met the O'Grady's criteria and the rational to indicate an auxiliary orthotopic liver transplantation was the acute classification without hemodynamic instability or renal failure in a patient with deterioration in consciousness.
Results:
The procedure improved liver function and decreased intracranial hypertension in the postoperative period.
Conclusion:
This technique can overcome some postoperative complications that are associated with partial grafts. As far as is known, this is the first case of auxiliary orthotopic liver transplantation in Brazil.
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