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Prevention of pneumococcal infections during mass gathering
Jaffar A Al-Tawfiq1,2, Ziad A Memish3
1a Johns Hopkins Aramco Healthcare ; Dhahran , Kingdom of Saudi Arabia.
Abstract:
The interest in mass gathering and its implications has been increasing due to globalization and international travel. The potential occurrence of infectious disease outbreaks during mass gathering is most feared. In this context, respiratory tract infections are of great concern due to crowding in a limited space which facilitates and magnifies the potential of disease spread among attendees. Pneumococcal disease is best described among pilgrims to Makkah and vaccination is one of the methods for the prevention of this disease. Pneumonia was described in a mass gathering with a prevalence of 4.8/100,000 pilgrims and contributes to 15-39% of hospitalizations. Various studies showed that 7-37% of pilgrims are 65 y of age or older. The uptake of pneumococcal vaccine among pilgrims is low at 5%. There is no available data to make strong recommendations for S. pneumoniae vaccination of all pilgrims, it is important that a high risk population receive the indicated vaccination. We reviewed the available literature on the burden of pneumococcal infections during mass gathering and evaluate the available literature on pneumococcal vaccinations for attendees of mass gathering.
Insights
Mass gatherings can increase infectious disease spread, particularly respiratory infections like pneumococcal disease. Vaccination is crucial for high-risk groups attending such events, despite low current uptake.
Area of Science:
- Public Health
- Epidemiology
- Infectious Diseases
Background:
- Mass gatherings, driven by globalization, pose risks for infectious disease outbreaks.
- Respiratory tract infections, such as pneumococcal disease, are a significant concern due to close proximity.
- Pilgrimages, like the Hajj, represent large-scale mass gatherings with documented pneumococcal disease burdens.
Purpose of the Study:
- To review the burden of pneumococcal infections in mass gathering attendees.
- To evaluate the efficacy and recommendations for pneumococcal vaccinations in this population.
Main Methods:
- Literature review of studies on pneumococcal infections during mass gatherings.
- Analysis of existing data on pneumococcal disease prevalence and vaccination rates among pilgrims.
- Assessment of risk factors and vaccination recommendations for attendees.
Main Results:
- Pneumococcal disease prevalence was reported at 4.8/100,000 pilgrims, contributing to 15-39% of hospitalizations.
- A significant portion (7-37%) of pilgrims are aged 65 or older, a high-risk group.
- Pneumococcal vaccine uptake among pilgrims is notably low (5%).
Conclusions:
- While data for universal vaccination recommendations is limited, high-risk populations attending mass gatherings should receive indicated pneumococcal vaccinations.
- Targeted vaccination strategies are essential to mitigate pneumococcal disease risks in vulnerable attendees.
- Further research is needed to establish comprehensive vaccination guidelines for mass gathering participants.
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