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[Evolution of contrast nephropathy in patients with chronic kidney disease undergoing a percutaneous coronary

Bibiana López-López1, María Juana Pérez-López, Andrés García-Rincón

  • 1Hospital de Especialidades Centro Médico Nacional La Raza,Instituto Mexicano del Seguro Social, Distrito Federal, México. dra-bibi@hotmail.com.

Revista Medica Del Instituto Mexicano Del Seguro Social
|July 16, 2015
PubMed

Insights

Contrast-induced nephropathy (CIN) occurred in 6.3% of high-risk chronic kidney disease patients undergoing percutaneous coronary intervention, despite preventive measures. Early nephrology assessment may reduce CIN frequency in these vulnerable patients.

Area of Science:

  • Nephrology
  • Cardiology
  • Radiology

Background:

  • The global shift towards chronic-degenerative diseases increases demand for contrast-enhanced procedures.
  • Contrast media pose a significant risk for acute kidney injury, especially in patients with chronic kidney disease (CKD).

Purpose of the Study:

  • To determine the incidence and progression of contrast-induced nephropathy (CIN) in ambulatory CKD patients undergoing percutaneous coronary intervention (PCI).

Main Methods:

  • A cohort of 32 CKD patients undergoing cardiac catheterization were monitored post-procedure.
  • Patients received preventive measures, and creatinine levels were assessed at 48 hours.
  • Descriptive statistics were used for analysis.

Main Results:

  • Of 1236 procedures, 32 met inclusion criteria; 96.87% had comorbidities like diabetes or hypertension.
  • 6.3% of patients developed CIN (creatinine >25% increase at 48 hours) despite prophylaxis.
  • No patients required renal replacement therapy.

Conclusions:

  • CIN incidence in high-risk CKD patients was lower than literature reports.
  • Pre-procedure nephrology assessment may contribute to reduced CIN rates.
Abstract

Keywords:
Acute kidney injuryContrast nephropathyCoronary angiography

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