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DNA Aptamer Based Nanodrugs: Molecular Engineering for Efficiency.

Sena Cansiz1, Liqin Zhang1, Cuichen Wu1,2

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Aptamer-based nanodrugs combine aptamers with nanomaterials for targeted cancer therapy. This review highlights recent advancements in these nanodrug systems for efficient drug delivery and controlled release.

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Area of Science:

  • Biomedical Research
  • Nanotechnology
  • Molecular Engineering

Background:

  • Cancer therapy has entered the
  • nano
  • era with novel nanomaterials.

Purpose of the Study:

  • To review recent achievements in aptamer-based nanodrug systems.
  • To highlight the potential of these systems for targeted cancer therapy.

Main Methods:

  • Combining aptamers' cancer-specific recognition with nanomaterials' properties.
  • Developing nanoscale drugs for targeted delivery and controlled release.

Main Results:

  • Emergence of various aptamer-based nanodrug systems.
  • Demonstration of "proof-of-concept" in early-stage studies.

Conclusions:

  • Aptamer-based nanodrugs offer significant potential for efficient and targeted cancer treatment.
  • Further development is expected to advance these systems towards clinical application.