Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[<sup>18</sup>F]FDG PET/MRI in Pediatric Focal Epilepsies.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2026
Same author

Precision pathways: optimising amyloid PET for sustainable Alzheimer's disease care.

Journal of neurology·2026
Same author

Non-Invasive Measurement of Cortical Plasticity in Brain Tumour Surgery: A Monocentric Experience of nTMS Mapping and Definition of Cognitive Reshaping Based on Tumour Histological Grade.

Cancers·2026
Same author

Aripiprazole‑induced akathisia associated with bilateral putaminal hypermetabolism on PET.

International clinical psychopharmacology·2026
Same author

Recent advances in synthetic virtual 3D endoscopy to assist in skull base surgery.

Expert review of neurotherapeutics·2026
Same author

Anomaly Detection for Structural and Functional Connectivity in Glioma Patients.

NMR in biomedicine·2026

Related Experiment Video

Updated: Apr 7, 2026

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

46.7K

Surgery on motor area metastasis.

Marta Rossetto1, Pietro Ciccarino1, Giuseppe Lombardi2

  • 1Department of Neurosurgery, Padua University Hospital, Azienda Ospedaliera di Padova, Via Giustiniani 2, 35128, Padova, Italy.

Neurosurgical Review
|July 17, 2015
PubMed
Summary
This summary is machine-generated.

Surgery for brain metastasis in the motor area can improve patient function. Tumor boundary irregularity strongly correlates with motor outcomes and resection extent, suggesting an infiltrative growth pattern.

Keywords:
Brain metastasisCentral areaFunctional outcomeKarnofsky Performance StatusMotor outcomeNeurophysiologic monitoring assisted surgery

More Related Videos

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE
06:04

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE

Published on: August 16, 2024

1.8K
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

4.4K

Related Experiment Videos

Last Updated: Apr 7, 2026

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

46.7K
Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE
06:04

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE

Published on: August 16, 2024

1.8K
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

4.4K

Area of Science:

  • Neurosurgery
  • Oncology
  • Neurology

Background:

  • The role of surgery in central area metastasis and its outcomes are debated.
  • Emerging data suggest tumor boundary irregularity influences brain metastasis outcomes.

Purpose of the Study:

  • To analyze predictive clinical and surgical factors for motor and functional outcomes in patients with solitary central area brain metastasis.
  • To investigate the impact of tumor boundary irregularity on surgical outcomes.

Main Methods:

  • Retrospective analysis of 47 patients with solitary central area metastasis undergoing surgery with neurophysiologic monitoring (2010-2013).
  • Inclusion criteria: Karnofsky Performance Status (KPS) ≥70, controlled systemic disease, no extra-cranial dissemination.
  • Outcomes assessed at 1-month follow-up, comparing motor and functional status with preoperative data, response to corticosteroids, resection extent, boundary irregularity, and tumor size.

Main Results:

  • Gross total resection achieved in 93.6% of cases.
  • In preoperative symptomatic patients, 55.5% improved motor function and 50% improved functional status (KPS). No worsening observed in asymptomatic patients.
  • Motor outcome strongly correlated with tumor boundary irregularity (p<0.05) and extent of surgical resection, but not with preoperative deficits, tumor volume, or corticosteroid response.

Conclusions:

  • Surgery with neurophysiologic monitoring can enhance motor and functional outcomes in selected patients with motor area metastasis.
  • Tumor volume is not a limiting factor for surgical intervention.
  • The correlation between outcome, resection rate, and boundary irregularity supports an infiltrative growth pattern for brain metastasis.