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In vitro immunologic features of Weimaraner dogs with neutrophil abnormalities and recurrent infections
C G Couto1, S Krakowka, G Johnson
1Department of Veterinary Clinical Sciences, Ohio State University, Columbus 43210.
Veterinary Immunology and Immunopathology
|November 30, 1989
Abstract:
In vitro evaluation of cellular and humoral immunity in Weimaraner dogs with recurrent infections and abnormal neutrophil function revealed significantly lower serum immunoglobulin (Ig) G and M concentrations than control dogs. Lymphocyte blastogenesis in response to three different mitogens, interleukin-1 and -2 production, natural killer (NK) cell activity, and in vitro IgG and IgM production were similar to those of control dogs.