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Updated: Apr 7, 2026

Rapid In Vivo Assessment of Adjuvant's Cytotoxic T Lymphocytes Generation Capabilities for Vaccine Development
Published on: June 19, 2018
Immunogenicity, Immunopathogenicity, and Immunotolerance in One Graph
1Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, Via Orabona, 4, Bari - 70125, Italy. darja.kanduc@uniba.it.
Abstract:
The concept according to which unique, rare and common sequences may define immunogenicity, immunopathogenicity and immunotolerance, respectively, is graphically illustrated using a melanoma-associated antigen, Melan-A/Mart-1, as a model. The final picture is consolidated by experimentally validated data from the scientific literature and may represent a concrete prelude to effective immunotherapies exempt from collateral autoimmune reactions.
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