Effects of Dabigatran on the Resolution of Left Ventricular Thrombus after Acute Myocardial Infarction

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Norihiko Ohashi1, Takenori Okada, Mio Uchida

  • 1Department of Cardiology, Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital, Japan.

Internal Medicine (Tokyo, Japan)
|July 17, 2015
PubMed

Insights

Left ventricular thrombus (LVT) after acute myocardial infarction (AMI) can cause embolic events. A case study shows dabigatran effectively treated LVT, suggesting it as a warfarin alternative for AMI patients.

Area of Science:

  • Cardiology
  • Pharmacology

Background:

  • Left ventricular thrombus (LVT) following acute myocardial infarction (AMI) poses a significant risk for embolic complications.
  • Warfarin is the traditional treatment for LVT but has limitations.

Observation:

  • A 78-year-old male patient with AMI and a history of paroxysmal atrial fibrillation developed LVT.
  • Transthoracic echocardiography confirmed a moderately sized LVT in the apex post-reperfusion therapy.

Findings:

  • Treatment with dabigatran for 18 days resulted in the complete resolution of the LVT.
  • This outcome suggests dabigatran's efficacy in managing LVT post-AMI.

Implications:

  • Dabigatran may serve as a viable alternative to warfarin for treating LVT in patients with AMI.
  • Further research is warranted to confirm dabigatran's role in LVT management post-myocardial infarction.

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