[Factors associated with control of hypertension in the cohort from the study of Cardiovascular Disease Risk in Castilla y León (RECCyL)]
Related Experiment Video
Updated: Apr 7, 2026

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
Published on: September 26, 2018
A García Iglesias1, J E Lozano Alonso1, R Álamo Sanz1
1Servicio de Información de Salud Pública, Dirección General de Salud Pública, Consejería de Sanidad de la Junta de Castilla y León, Valladolid, España.
Insights
More than half of individuals with hypertension have uncontrolled blood pressure. Diabetes, obesity, and smoking are key factors linked to poor blood pressure control in the Castilla y León population.
Area of Science:
- Public Health
- Cardiology
- Epidemiology
Background:
- Cardiovascular diseases pose a significant public health challenge due to high mortality and healthcare costs.
- Effective blood pressure control is crucial for mitigating cardiovascular disease risks.
Purpose of the Study:
- To assess blood pressure control levels in a population cohort in Castilla y León.
- To identify factors associated with uncontrolled hypertension.
Main Methods:
- A cohort study involving 4013 individuals aged 15+ in 2004, with follow-up in 2009 on 2954 participants.
- Hypertension defined as blood pressure <140/90 mm Hg; logistic regression used to identify associated factors.
- Included medical history, physical exams, and blood tests.
Main Results:
- 55.9% of the cohort exhibited uncontrolled blood pressure levels, with no gender-based differences.
- Independent predictors of uncontrolled hypertension included diabetes (OR 3.87), obesity (OR 1.58), smoking (OR 1.49), and prior systolic blood pressure (OR 1.13 per 5 mm Hg).
- Age was not found to be a statistically significant factor.
Conclusions:
- Over half of hypertensive patients in the study population have inadequate blood pressure control.
- Findings highlight key risk factors for poor hypertension management in Castilla y León.
- Results can inform targeted primary and secondary prevention strategies for cardiovascular health.
Introduction:
Cardiovascular diseases and related risk factors suppose a challenge to public health due to the mortality and health costs involved. This study has aimed to assess the blood pressure control in a population cohort and to identify the factors associated with poor control.
Material And Methods:
A cardiovascular health examination was carried out in a random sample of 4013 individuals aged 15 years and above who were living in Castilla y Leon in 2004. The study included the medical history, physical exam and blood tests. A new health study was performed in 2009, including 2954 people from the initial sample, 1306 of whom were patients with hypertension. Strict blood pressure control was defined as <140/90 mm Hg. Bivariate analysis was performed and odds ratio was calculated by a regression logistic model.
Results:
Blood pressure levels were above the established levels in 55.9%, without differences between men and women. The regression model showed that diabetes, obesity, smoking habit and previous systolic blood pressure values, with odds ratio of 3.87, 1.58, 1.49 and 1.13 per 5 mm Hg, respectively, are independently associated with uncontrolled blood pressure. Age did not show statistical significance.
Conclusion:
More than half of the patients with hypertension are not well controlled. This study provides information about the characteristics of the patients with poor control of hypertension in Castilla y León, which will allow policy makers to develop new primary and secondary prevention activities.
Related Concept Videos
Factors affecting Blood pressure
Physiological Factors:
Hypertension and Regulation of Blood Pressure
Hypertension II: Pathophysiology
Hypertension III: Clinical Manifestations and Diagnostic Studies
Hormonal Regulation of Blood Pressure
Epinephrine and Norepinephrine
The adrenal medulla releases epinephrine and norepinephrine, catecholamines that enhance and extend the sympathetic or "fight or flight" physiological response. These hormones escalate heart rate and the force of contraction...
Hypertension IV: Drug Therapy and Lifestyle Modifications

