Optimal blood pressure targets in 2014 - Does the guideline recommendation match the evidence base?

C L Alviar1, S Bangalore1, F H Messerli2

  • 1New York University Langone Medical Center, New York, NY, United States.

Insights

Recent arterial hypertension guidelines lack consensus on blood pressure targets. This review critically examines the evidence supporting these differing recommendations for hypertension management.

Area of Science:

  • Cardiology
  • Internal Medicine
  • Clinical Practice Guidelines

Background:

  • Arterial hypertension is a major cardiovascular risk factor.
  • Multiple scientific societies have issued practice guidelines for hypertension diagnosis and management.
  • Discrepancies exist among guidelines, particularly regarding target blood pressure levels.

Purpose of the Study:

  • To review and critically analyze recent practice guidelines for arterial hypertension.
  • To evaluate the evidentiary basis for the recommended blood pressure targets in hypertension management.
  • To identify areas of consensus and divergence in hypertension treatment guidelines.

Main Methods:

  • Systematic review of recently published practice guidelines for arterial hypertension.
  • Critical appraisal of the scientific evidence cited within these guidelines.
  • Comparative analysis of recommended blood pressure targets and management strategies.

Main Results:

  • Significant variation exists in recommended blood pressure targets across different hypertension guidelines.
  • The evidence supporting specific blood pressure targets is often debated and subject to interpretation.
  • Lack of clear consensus complicates clinical decision-making for healthcare providers.

Conclusions:

  • Current arterial hypertension guidelines present a fragmented approach to blood pressure targets.
  • Further research is needed to establish definitive, evidence-based blood pressure targets for optimal hypertension management.
  • Clinical practice requires careful consideration of guideline variations and underlying evidence.

Related Concept Videos

Hypertension I: Introduction01:28

Hypertension I: Introduction

Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
1.2K
Factors affecting Blood pressure01:28

Factors affecting Blood pressure

Several physiological and lifestyle factors influence blood pressure (BP). Understanding these factors is crucial as they are significant in patient education and blood pressure management.
Physiological Factors:
7.7K
Assessment of blood pressure in brachial artery(one-step method)01:15

Assessment of blood pressure in brachial artery(one-step method)

This procedural guide systematically measures blood pressure using an oscillometric digital sphygmomanometer, emphasizing accuracy, patient safety, and comfort.
Prepare for the Procedure:
1.4K
Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
4.8K
Hypertension IV: Drug Therapy and Lifestyle Modifications01:28

Hypertension IV: Drug Therapy and Lifestyle Modifications

Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...
851
Blood Pressure01:30

Blood Pressure

Blood pressure (BP) is the pressure or force of blood exerted on the artery's walls as it circulates through the body. It is essential for maintaining blood flow throughout the body.
The average BP in an adult is typically around 120/80 mmHg (millimeters of mercury). In this measurement, the numerator (120) indicates the systolic pressure, which is the pressure in the arteries during the contraction of the heart's ventricles as blood is expelled. The denominator (80) represents the...
5.6K