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10:10
Genetic Engineering of an Unconventional Yeast for Renewable Biofuel and Biochemical Production
Published on: September 20, 2016
15.4K
Oleaginous yeast: a value-added platform for renewable oils
Kyle V Probst1,2, Leslie R Schulte1,3, Timothy P Durrett4
1a IGERT in Biorefining .
Critical Reviews in Biotechnology
|July 17, 2015
Summary
Yeast single cell oil (SCO) offers a renewable, non-crop alternative for oleochemicals. Cost-competitiveness can be achieved through improved bioprocessing, nutrient utilization, and biotechnological advancements for a sustainable bio-economy.
Area of Science:
- Biotechnology
- Industrial Microbiology
- Sustainable Chemistry
Background:
- Single cell oil (SCO) from yeast is a renewable, non-crop-based resource for bio-based oleochemicals.
- Current SCO production is not cost-competitive with petroleum or crop-based oils.
- Advancements are needed to establish SCO as a viable platform in the bio-based economy.
Purpose of the Study:
- To review key biochemical pathways for storage lipid synthesis in yeast.
- To explore strategies for improving SCO yield and production efficiency.
- To discuss challenges and advantages of SCO commercialization.
Main Methods:
- Literature review of biochemical pathways for lipid synthesis.
- Analysis of biotechnological approaches like systems biology and metabolic engineering.
- Examination of bioprocessing techniques and downstream processing.
Main Results:
- Identified key pathways for storage lipid accumulation in yeast.
- Outlined potential strategies for enhancing SCO yield through genetic and process optimization.
- Discussed various bioprocessing and downstream techniques for SCO recovery.
Conclusions:
- Optimizing nutrient sources and downstream processes is crucial for cost-competitiveness.
- Biotechnological advancements are key to realizing a commercial SCO platform.
- SCO presents a sustainable alternative for oleochemical production.
Keywords:
Biofuelfatty acidfermentationintegrated biorefinerylignocellulosic biomasslipidoleochemicalsingle cell oiltriacylglycerideMore Related Videos
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