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Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
Published on: January 29, 2018
Effect of serum cholesterol on bone mineral density in normal-weight children and adolescents
Abstract:
We investigated whether there is a relationship between serum cholesterol and bone mineral density (BMD), independent of BMI in children and adolescents. This study was based on data from the KNHANES 2009-2010. The data for 1557 children and adolescents were analyzed and classified into three groups: underweight, normal-weight, and overweight. We analyzed the relationships between serum cholesterol and BMD z-scores. Whole body BMD z-score was revealed as an inverse association with the serum cholesterol quartile in only normal-weight group (p=0.008). Serum cholesterol level correlated more inversely with BMD z-score in normal-weight boys (r2=0.040, p=0.002) than in girls (r2=0.019, p=0.042). Multivariate regression analysis identified serum cholesterol as association with BMD in normal-weight (r2=0.020, p=0.002). Serum cholesterol concentration may be a detrimental risk factor for BMD in normal-weight children and adolescents independent of BMI.
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