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Published on: August 16, 2018
New flavonoid and pentacyclic triterpene from Sesamum indicum leaves
Nguyen Tien Dat1, Nguyen Hai Dang1, Le Nguyen Thanh1
1a Institute of Marine Biochemistry, Vietnam Academy of Science and Technology , 18-Hoang Quoc Viet, Cau Giay , Hanoi , Vietnam.
Abstract:
Two new and one known compounds were isolated from the methanol extract of Sesamum indicum leaves. By means of spectroscopic methods, their structures were elucidated and identified to be 3-epibartogenic acid (1), kaempferol 3-O-[2-O-(trans-p-coumaroyl)-3-O-α-L-rhamnopyranosyl]-β-D-glucopyranoside (2) and epigallocatechin (3). Compound 1 and 3 strongly inhibited α-amylase with the IC50 values of 146.7 and 303.9 μM, respectively, in comparison with acarbose (IC50 124.0 μM).
