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Diagnosis of Dissection of the Coronary Artery Dissection by Multidetector Computed Tomography: A Comparative Study

Yibo Sun1, Dingbiao Mao, Fang Lu

  • 1From the Departments of *Radiology and †Cardiology, Huadong Hospital, Fudan University, Shanghai, China.

Journal of Computer Assisted Tomography
|July 17, 2015
PubMed

Insights

Multidetector computed tomography (MDCT) angiography is a superior tool for detecting coronary artery dissection (DCA) compared to coronary angiology (CAG). MDCT demonstrated higher sensitivity and specificity in diagnosing DCA.

Area of Science:

  • Cardiovascular Imaging
  • Diagnostic Radiology

Background:

  • Coronary artery dissection (DCA) is a critical condition requiring accurate diagnosis.
  • Traditional diagnostic methods may have limitations in sensitivity and specificity.

Purpose of the Study:

  • To evaluate the diagnostic performance of multidetector computed tomography (MDCT) angiography for detecting coronary artery dissection (DCA).
  • To compare MDCT's diagnostic accuracy against coronary angiology (CAG).

Main Methods:

  • Retrospective review of 36 DCA patients and 34 controls.
  • Intravascular ultrasound served as the gold standard.
  • Independent review of MDCT angiography and CAG images using a 5-point scale.
  • Receiver operating characteristic (ROC) analysis for performance comparison.

Main Results:

  • MDCT angiography showed significantly superior performance (AZ = 0.9943) compared to CAG (AZ = 0.8411).
  • MDCT achieved higher sensitivity (98.6% vs 77.8%), specificity (89.7% vs 79.4%), and negative predictive value (98.4% vs 77.1%) for DCA detection.

Conclusions:

  • MDCT angiography is a highly sensitive and specific imaging technique for diagnosing coronary artery dissection.
  • MDCT offers improved diagnostic accuracy over conventional coronary angiology for DCA.
Abstract

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