Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Immunodeficiency Diseases

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...

Vaccinations

Vaccinations

Methods Of Healthcare Delivery System

Methods Of Healthcare Delivery System

At the different levels of the healthcare system, we see varying methods of healthcare used. These methods include managed care systems, case management, and primary healthcare.
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...

Development of Immunocompetence

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...

Primary Healthcare Services

Primary Healthcare Services

Primary care promotes wellness and prevents disease. This care includes health promotion, education, protection (such as immunizations), early disease screening, and environmental considerations. Settings providing this type of healthcare include physician offices, public health clinics, school nursing, and community health nursing.
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...

Tumor Immunotherapy

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Effects of ginger-loaded chitosan nanoparticles on growth, morphological and biochemical attributes of Sesamum indicum L.

PloS one·2026

Same author

Simultaneous measurement of linear and angular displacement sensor using POF based on macro-bend loss.

Scientific reports·2026

Same author

Multi-Species Probiotics Improve Health Performance and Alleviate Stress Responses of Rohu (Labeo rohita) in Inland Brackish Water Ponds.

Probiotics and antimicrobial proteins·2026

Same author

Bringing legislation to life: Navigating intersectional barriers in implementing the Sindh Empowerment of Persons with Disabilities Act (2018) for the healthcare of children with disabilities.

PLOS global public health·2026

Same author

Many-Body Benchmark of Electronic Charge and Spin Densities for Li<sub>1-<i>x</i></sub>NiO<sub>2</sub>.

Journal of chemical theory and computation·2026

Same author

Tackling the global health research financing emergency to sustain national health research ecosystems.

Lancet (London, England)·2026

Search research articles

Related Experiment Video

Updated: Apr 6, 2026

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen

Published on: May 12, 2023

ENHANCED IMMUNIZATION COVERAGE THROUGH INTERVENTIONS FOR CHILDHOOD CLUSTER DISEASES IN DEVELOPING COUNTRIES.

Sheh Mureed, Ratana Somronghtong, Ramesh Kumar

Journal of Ayub Medical College, Abbottabad : JAMC

|July 18, 2015

Summary

Professional interventions significantly boost childhood immunization coverage in developing nations, particularly for DTP and measles vaccines. This public health strategy is crucial for reducing child morbidity and mortality globally.

More Related Videos

Murine Model of Epicutaneously-Induced Immunomodulation

Murine Model of Epicutaneously-Induced Immunomodulation

Published on: June 24, 2025

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Published on: October 31, 2010

Related Experiment Videos

Last Updated: Apr 6, 2026

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen

Fabrication of Pulsatile Polymeric Microparticles Encapsulating Rabies Antigen

Published on: May 12, 2023

Murine Model of Epicutaneously-Induced Immunomodulation

Murine Model of Epicutaneously-Induced Immunomodulation

Published on: June 24, 2025

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Published on: October 31, 2010

Area of Science:

Public Health
Epidemiology
Global Health

Background:

Childhood immunization is a critical public health intervention to reduce mortality.
Developing countries face challenges in achieving full immunization coverage due to various constraints.
Identifying effective interventions is vital for improving vaccination rates in vulnerable populations.

Purpose of the Study:

To systematically review and identify effective interventions for increasing childhood immunization coverage in developing countries.
To analyze the impact of interventions on vaccination rates for specific diseases.

Main Methods:

Systematic review adhering to PRISMA guidelines.
Searched PubMed, Scopus, Cochrane, Medline, and ISI for relevant studies.
Included randomized controlled trials and quasi-experimental studies, assessed using the Down and Black checklist.

Main Results:

10 studies involving 16,570 articles analyzed showed interventions significantly increased vaccine coverage for childhood diseases (OR 2.136, p <0.05).
Interventions had a more prominent effect on DTP (OR 2.397, p<0.05) and measles (OR 2.628, p<0.05) coverage.
The effect was less pronounced for polio and full vaccination schedules.

Conclusions:

Professional interventions are effective in improving child immunization coverage for cluster diseases in developing countries.
Diphtheria, tetanus, and pertussis (DTP) and measles vaccines showed the most significant impact.
These findings underscore the importance of targeted interventions to enhance public health outcomes.