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Updated: Apr 6, 2026

Murine Precision-Cut Liver Slices as an Ex Vivo Model of Liver Biology
Published on: March 14, 2020
Fast-track, ambulatory ultrasound-guided Tru-Cut liver biopsy is feasible and cost-efficient
Chenxi Huang1, Torben Lorentzen, Bjørn Skjoldbye
1Gastroenheden D, Herlev Hospital, Herlev Ringvej 75, 2730 Herlev, Denmark. chenxihuang@msn.com.
Introduction:
Most institutions perform percutaneous liver biopsy with a post-biopsy patient observation period lasting up to eight hours, which is resource-demanding. This study aimed to evaluate the safety of liver biopsy performed in a fast-track set-up with an only one-hour post-biopsy observation time.
Methods:
Patients referred to our institution underwent fast-track ultrasound-guided 18-gauge Tru-Cut liver biopsy procedures. Each single biopsy procedure was followed by a post-procedure observational period of one hour and an additional focused assessment with sonography for trauma before patient discharge. All patients underwent a clinical follow-up programme at revisit in order to register any delayed onset of major complications.
Results:
Out of 200 completed biopsy procedures, two major complications were registered post biopsy and they were treated appropriately. All patients were safely discharged from our institution. No fatality or long-term complications were found during this study.
Conclusion:
The fast-track approach reported herein is a feasible option when adequate patient information is given. Besides the obvious, positive effect on patient logistics and departmental throughput, this approach may also reduce diagnostic work-up time and bring financial benefits. Therefore, we encourage the use of this approach in institutions comparable to our own.
Funding:
not relevant.
Trial Registration:
not relevant.
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