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Central auditory processing in patients with spinocerebellar ataxia
Bianca Simone Zeigelboim1, Hugo Amilton Santos de Carvalho1, Hélio Afonso Ghizoni Teive2
1University Tuiuti of Paraná, Otoneurology Research Center, Curitiba, Brazil.
Hearing Research
|July 18, 2015
Summary
Central auditory processing disorders (CAPD) are common in spinocerebellar ataxias (SCAs). Most patients showed deficits in the Standard Spondaic Word (SSW) and Random Gap Detection Test (RGDT), indicating issues with sound processing and timing.
Area of Science:
- Neuroscience
- Audiology
- Genetics
Background:
- Autosomal dominant spinocerebellar ataxias (SCAs) are neurodegenerative diseases causing progressive cerebellar ataxia.
- Central auditory functioning in SCA patients is not well-documented.
- This study investigates central auditory processing disorders (CAPD) across different SCA subtypes.
Purpose of the Study:
- To assess the prevalence and characteristics of CAPD in patients with various types of SCAs.
- To evaluate auditory processing using specific diagnostic tests.
- To highlight the importance of CAPD assessment in SCA patient management.
Main Methods:
- Retrospective cross-sectional study of 43 SCA patients.
- Evaluations included audiology, Brainstem Auditory Evoked Potential (BAEP), acoustic immittance, Standard Spondaic Word (SSW), and Random Gap Detection Test (RGDT).
Main Results:
- Significant alterations were found in audiometric (32.5%), BAEP (46.5%), SSW (55%), and RGDT (75%) tests.
- Most patients exhibited SSW deficits (bilateral predominance) and impaired RGDT performance.
- Specific SCA subtypes showed varying degrees of auditory processing deficits.
Conclusions:
- A majority of SCA patients experience CAPD, particularly affecting binaural integration and temporal resolution.
- CAPD assessment is crucial for comprehensive therapeutic follow-up in SCA patients.
- Findings underscore the need to consider auditory function in the clinical management of SCAs.
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