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Comparison of swept source optical coherence tomography and spectral domain optical coherence tomography in
Daniel S W Ting1, Gemmy C M Cheung1, Laurence S Lim1
1Singapore National Eye Center, Singapore Health Service (SingHealth), Singapore, Singapore.
Background:
Swept source optical coherence tomography (SS-OCT, Topcon Medical System, Japan) is known to have longer wavelength than spectral domain OCT (SD-OCT, Spectralis, Heidelberg Engineering, Germany), allowing a deeper penetration into retina and choroidal layers. This objective of this study was to compare the visibility of retinal and choroidal features in polypoidal choroidal vasculopathy (PCV) using SS-OCT and SD-OCT.
Design:
This study employs prospective comparative observational case series in Singapore National Eye Center.
Participants:
There were 20 eyes (20 patients) with PCV confirmed with indocyanine green angiogram.
Methods:
Six pre-specified OCT parameters (presence of polyps, sharp pigment epithelial detachment [PED] peak, notched PED and visibility of full maximum height of PED, inner segment/outer segment [IS/OS] line and choroid-scleral interface [CSI]) were graded using SS-OCT and SD-OCT.
Main Outcome Measures:
The Kappa statistics between the two imaging modalities were calculated.
Results:
Both SS-OCT and SD-OCT were able to detect polypoidal lesions in the majority of eyes (90% and 85%, respectively). However, SS-OCT had better detection for CSI and IS/OS lines (CSI: 80% vs 45%, P = 0.05; IS/OS line: 65% vs 45%, P = 0.34). For sharp PED peak, notched PED, ability to visualize the full PED height and retinal pigment epithelial line, both OCT machines were able to detect in ≥80% of the eyes.
Conclusion:
In conclusion, SS-OCT and SD-OCT appeared to be similarly effective at detecting most features associated with PCV. However, SS-OCT is more superior in detecting the CSI.
