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The Resting Membrane Potential

The Resting Membrane Potential

Resting Membrane Potential

Resting Membrane Potential

The relative difference in electrical charge, or voltage, between the inside and the outside of a cell membrane, is called the membrane potential. It is generated by differences in permeability of the membrane to various ions and the concentrations of these ions across the membrane.
The Inside of a Neuron is More Negative
The membrane potential of a cell can be measured by inserting a microelectrode into a cell and comparing the charge to a reference electrode in the extracellular fluid. The...

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Related Experiment Video

Updated: Apr 6, 2026

Induction of an Isoelectric Brain State to Investigate the Impact of Endogenous Synaptic Activity on Neuronal Excitability In Vivo

Induction of an Isoelectric Brain State to Investigate the Impact of Endogenous Synaptic Activity on Neuronal Excitability In Vivo

Published on: March 31, 2016

Ketamine inside neurons?

Henry A Lester¹, Luke D Lavis¹, Dennis A Dougherty¹

¹From the Division of Biology and Biological Engineering and the Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, Calif.; and the Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Va.

The American Journal of Psychiatry

|July 18, 2015

Summary

No abstract available in PubMed .

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