Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

897
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
897
Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

636
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
636
Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

1.8K
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
1.8K
Autoimmune Disorders01:29

Autoimmune Disorders

2.2K
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
2.2K
Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

1.5K
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
1.5K
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

496
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
496

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Drainage for fluid collections post pancreatic surgery and acute pancreatitis: similar but different?

Clinical endoscopy·2024
Same author

Metal versus plastic stents for walled-off pancreatic necrosis: much alike, then which?

Endoscopy·2024
Same author

Role of advanced endoscopy in the management of inflammatory digestive diseases (pancreas and biliary tract).

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society·2024
Same author

Case of hilar cholangiocarcinoma with a distal skip lesion detected by cholangioscopy.

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society·2024
Same author

Successful retrieval of a migrated stent in the pancreatic duct after endoscopic ultrasound-guided pancreaticogastrostomy with peroral pancreatoscopy.

Endoscopy·2024
Same author

Risk of recurrence with or without plastic stent after EUS-guided treatment of peripancreatic fluid collections: A systematic review and meta-analysis.

Endoscopy international open·2024

Related Experiment Video

Updated: Apr 6, 2026

Isolation of Human Islets from Partially Pancreatectomized Patients
11:10

Isolation of Human Islets from Partially Pancreatectomized Patients

Published on: July 30, 2011

17.1K

Association between autoimmune pancreatitis and malignancy.

Kenji Hirano1, Hiroyuki Isayama, Minoru Tada

  • 1Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan, khirano-tky@umin.ac.jp.

Clinical Journal of Gastroenterology
|July 18, 2015
PubMed
Summary

Autoimmune pancreatitis (AIP) shows no conclusive link to pancreatic cancer, but some studies suggest a higher risk. Research also indicates AIP may not increase overall malignancy risk, though a paraneoplastic syndrome link is proposed.

More Related Videos

Ultrasound-Guided Orthotopic Implantation of Murine Pancreatic Ductal Adenocarcinoma
06:21

Ultrasound-Guided Orthotopic Implantation of Murine Pancreatic Ductal Adenocarcinoma

Published on: November 19, 2019

12.5K
Oncogene Expression Analysis with Alterations in pH in a Pancreatic Ductal Cell Line
06:24

Oncogene Expression Analysis with Alterations in pH in a Pancreatic Ductal Cell Line

Published on: April 11, 2025

994

Related Experiment Videos

Last Updated: Apr 6, 2026

Isolation of Human Islets from Partially Pancreatectomized Patients
11:10

Isolation of Human Islets from Partially Pancreatectomized Patients

Published on: July 30, 2011

17.1K
Ultrasound-Guided Orthotopic Implantation of Murine Pancreatic Ductal Adenocarcinoma
06:21

Ultrasound-Guided Orthotopic Implantation of Murine Pancreatic Ductal Adenocarcinoma

Published on: November 19, 2019

12.5K
Oncogene Expression Analysis with Alterations in pH in a Pancreatic Ductal Cell Line
06:24

Oncogene Expression Analysis with Alterations in pH in a Pancreatic Ductal Cell Line

Published on: April 11, 2025

994

Area of Science:

  • Gastroenterology
  • Oncology
  • Immunology

Background:

  • Chronic inflammation is linked to malignancy, including in gastroenterology.
  • Chronic pancreatitis is associated with pancreatic cancer.
  • The relationship between autoimmune pancreatitis (AIP) and malignancy is under investigation.

Purpose of the Study:

  • To discuss the association between autoimmune pancreatitis (AIP) and pancreatic cancer.
  • To explore the link between AIP and overall cancer risk.
  • To evaluate the hypothesis of AIP as a paraneoplastic syndrome.

Main Methods:

  • Literature review and discussion of existing studies on AIP and malignancy.
  • Analysis of reports on AIP and pancreatic cancer risk.
  • Examination of Japanese studies on AIP and total malignancies.

Main Results:

  • No conclusive evidence links AIP directly to pancreatic cancer, though some studies suggest an elevated risk.
  • Two Japanese reports found no increased risk of total malignancies due to chronic inflammation in AIP.
  • One study proposed AIP might be a paraneoplastic syndrome, with cancers appearing shortly after AIP diagnosis.

Conclusions:

  • The association between AIP and pancreatic cancer remains inconclusive.
  • Current evidence does not support AIP-related chronic inflammation increasing overall malignancy risk.
  • Further research is needed to investigate the paraneoplastic syndrome hypothesis in AIP.