Comparison of CT and MR angiography in evaluation of peripheral arterial disease before endovascular intervention
Alessandro Cina1, Carmine Di Stasi1, Vittorio Semeraro2
1Department of Radiological Sciences, "Agostino Gemelli" Hospital, Catholic University, Rome, Italy.
Insights
Multidetector computed tomography angiography (MDCTA) is more accurate than magnetic resonance angiography (MRA) for assessing peripheral arterial disease, especially in infrapopliteal segments. MDCTA offers higher confidence and shorter examination times for endovascular intervention planning.
Area of Science:
- Vascular Surgery
- Diagnostic Imaging
- Interventional Radiology
Background:
- Peripheral arterial disease (PAD) diagnosis relies on imaging techniques like MDCTA and MRA for treatment selection.
- No direct comparative studies exist for MDCTA versus MRA in PAD patients eligible for both modalities before endovascular treatment.
Purpose of the Study:
- To compare the diagnostic performance of MDCTA and MRA in patients with PAD undergoing endovascular intervention.
Main Methods:
- A prospective study compared 64-slice MDCTA and 1.5T MRA in 35 PAD patients.
- Both techniques were used to determine TASC II and runoff severity scores.
- Selective angiography served as the reference standard for accuracy assessment.
Main Results:
- MDCTA and MRA showed high accuracy in aorto-iliac (0.92) and femoro-popliteal (MDCTA 0.94, MRA 0.90) segments.
- MDCTA demonstrated superior accuracy in infrapopliteal segments (0.96 vs. 0.9) and runoff assessment (0.92 vs. 0.85).
- MDCTA provided greater confidence and reduced examination time.
Conclusions:
- MDCTA is a reliable first-line investigation for PAD patients considered for endovascular procedures.
- It is particularly recommended when severe infrapopliteal disease is suspected based on clinical or duplex ultrasound findings.
Background:
Multidetector computed tomography angiography (MDCTA) and magnetic resonance angiography (MRA) are accurate techniques for selecting patients with peripheral arterial disease for surgical and endovascular treatment. No studies in the literature have directly compared MDCTA and MRA to establish which one should be employed, in patients suitable for both techniques, before endovascular treatment.
Purpose:
To compare diagnostic performance of MDCTA vs MRA before endovascular intervention.
Material And Methods:
We prospectively compared MDCTA (64 slices scanner) and MRA (1.5 T scanner; 3D gadolinium-enhanced bolus-chase acquisition plus time resolved acquisition on calves) to stratify 35 patients according to the TASC II score and a runoff severity score. We also evaluated the accuracy of both techniques in each arterial segment. Selective angiography performed during the treatment was the standard of reference.
Results:
MDCTA and MRA accurately classify disease in the aorto-iliac (accuracy 0.92 for MDCTA and MRA) and femoro-popliteal (MDCTA 0.94, MRA 0.90) segments. MDCTA was more accurate in stratifying disease in the infrapopliteal segments (0.96 vs. 0.9) and in assessing the impairment of runoff arteries (0.92 vs. 0.85) at per-segment analysis. MDCTA showed a higher confidence and a shorter examination time.
Conclusion:
Our results suggest that MDCTA can be considered as a first-line investigation in patients being candidates for endovascular procedures when clinical history or duplex sonographic evaluation are indicative of severe impairment of the infrapopliteal segment.
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