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Hepatic angiomyolipoma growing to cause epigastric discomfort: a case report
Masahiko Yamaguchi1, Yoshihiko Ueda, Takao Suzuki
1Second Department of Surgery, Dokkyo Medical School Koshigaya Hospital, Koshigaya, 343-8555, Japan, myamag@hotmail.co.jp.
Abstract:
We report herein a case of hepatic angiomyolipoma growing to cause epigastric discomfort. A 33-year-old man was referred for excisional operation of hepatic hypervascular tumor, complaining of epigastric discomfort. The tumor had enlarged from the time 3 years before when the tumor was diagnosed as hepatic hemangioma in the lateral segment. Partial hepatectomy with tumor resection was carried out. Pathological diagnosis was confirmed as hepatic angiomyolipoma with a finding of enriched vessels, extramedullary hematopoiesis, fatty tissue, and most epithelioid cells immunoreactive to HMB-45. Further analysis also revealed positive staining cells for granulocyte colony-stimulating factor. It was suggested that growth of hepatic angiomyolipoma in this case might be caused by extramedullary hematopoiesis induced by granulocyte colony-stimulating factor.
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