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Related Experiment Video

Updated: Apr 6, 2026

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[Medication-overuse headache].

Máté Magyar1, Boglárka Hajnal, Tamás Gyüre

  • 1Neurológiai Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Balassa u. 6., 1083.

Orvosi Hetilap
|July 18, 2015
PubMed
Summary

Medication-overuse headache (MOH) affects 1-2% of people. Regular painkiller use over 10 days/month can trigger MOH, necessitating awareness in patients with increased headache frequency.

Keywords:
fejfájásfájdalomcsillapító-túlhasználatheadache disordersmedication-overuse headache

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Area of Science:

  • Neurology
  • Pharmacology

Context:

  • Medication-overuse headache (MOH) impacts 1-2% of the global population.
  • It is frequently observed in females aged 40-50.
  • Risk factors include smoking, obesity, depression, and anxiety.

Purpose:

  • To elucidate the complex pathomechanism of MOH.
  • To outline essential treatment strategies and emphasize prevention.
  • To highlight the critical role of general practitioners in managing MOH.

Summary:

  • MOH arises from regular analgesic use (≥10 days/month), often presenting as increased headache frequency.
  • Pathomechanisms involve genetic, biological, psychological, and behavioral factors.
  • Treatment requires withdrawal of the offending agent, management of withdrawal symptoms, preventative strategies, and patient education.

Impact:

  • Effective management and prevention of MOH are crucial due to high relapse rates (30-40%).
  • Early identification and intervention by healthcare providers can significantly improve patient outcomes.
  • Understanding MOH pathogenesis aids in developing targeted therapeutic approaches.