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Highly-efficient T4 DNA ligase-based SNP analysis using a ligation fragment containing a modified nucleobase at the
Eui Kyoung Jang1, Munhee Yang, Seung Pil Pack
1Department of Biotechnology and Bioinformatics, Korea University, Jochiwon, Sejong 339-700, Korea. spack@korea.ac.kr.
Chemical Communications (Cambridge, England)
|July 18, 2015
Abstract:
A highly accurate ligase-based SNP analysis was developed by using modified base-end downstream ligation fragments as detection probes, which can clearly distinguish C/T SNP types without any "false-positive" results.
