[P-matrix spectrophotometric determination of 6 components contained in compound reserpine tablets]

P-matrix method has been developed for the simultaneous determination of vitamin B1, vitamin B6, chlordiazepoxide, dihydralazins sulfate, promethazine hydrochloride and hydrochlorothiazide contained in compound reserpine tablets consisting of 10 components. The optimal wave-length for measurement was successfully selected based on the principle of condition number. The influence of experimental error, number of wavelength and condition number deviation of component concentration from formula were discussed. The average recoveries varied from 97-103% with CV less than or equal to 9.5% (n = 11).