Related Experiment Video
Updated: Apr 6, 2026
08:45
New Thrombectomy Technique for Total Portal Vein Thrombosis in Liver Transplantation
Published on: June 27, 2025
1.9K
Portal vein thrombosis associated with ischemic colitis
Akitoshi Kobayashi1, Hideaki Mizumoto2, Takeshi Ando2
1Department of Gastroenterology, Funabashi Municipal Medical Center, 1-21-1 Kanasugi, Funabashi, Chiba, 274-8588, Japan. konino@par.odn.ne.jp.
Clinical Journal of Gastroenterology
|July 21, 2015
Summary
Ischemic colitis can lead to portal vein thrombosis (PVT), causing hepatic dysfunction. Early detection and anticoagulation therapy are crucial for managing this serious complication, even with normal coagulation tests.
Area of Science:
- Gastroenterology
- Vascular Medicine
- Hepatology
Background:
- Ischemic colitis presents with abdominal pain and hematochezia.
- Hepatic dysfunction can be a complication of ischemic colitis.
- Portal vein thrombosis (PVT) is a serious condition affecting blood flow to the liver.
Purpose of the Study:
- To report a case of ischemic colitis associated with portal vein thrombosis (PVT).
- To highlight the importance of considering PVT in patients with ischemic colitis and hepatic dysfunction.
- To discuss the diagnostic and therapeutic approach for this combined condition.
Main Methods:
- Case report of a 52-year-old male.
- Diagnostic tools included colonoscopy, blood tests, abdominal ultrasonography (US), and computed tomography (CT).
- Treatment involved anticoagulation therapy for PVT.
Main Results:
- The patient was diagnosed with ischemic colitis and PVT.
- US and CT revealed thrombus in the portal vein, with diminished but persistent thrombus after treatment.
- Hepatic dysfunction and liver atrophy were noted.
- Anticoagulation therapy was initiated for PVT.
Conclusions:
- Ischemic colitis can be complicated by PVT, leading to hepatic dysfunction.
- PVT should be considered in patients with ischemic colitis and unexplained hepatic dysfunction.
- Prompt diagnosis and management, including anticoagulation, are essential for improving outcomes in such cases.
Related Concept Videos
01:30Venous Thrombosis I: Introduction
702
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
702
01:27Inflammatory Bowel Disease I: Ulcerative Colitis
1.4K
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
1.4K
01:20Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
439
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
439
01:29Venous Thrombosis III: Interprofessional Care
466
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
466
01:24Esophageal Varices-I: Introduction
2.1K
Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
2.1K
01:17Chronic Bowel Disorders: Introduction
930
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
930