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Two new isoaurones derivatives from Callistephus chinensis flower
Xiao-shu Zhang1,2, Jia-qing Cao1,2, Guo-hui Shi3
1a School of Traditional Chinese Medicine, Shenyang Pharmaceutical University , Shenyang 110016 , People's Republic of China.
Abstract:
Two new isoaurones derivatives were obtained from Callistephus chinensis flower. Their structures were elucidated on the basis of extensive spectroscopic analyses. Both of the new compounds were evaluated cytotoxic activity. Phytochemical investigation of Callistephus chinensis flower led to the isolation of two new isoaurones derivatives (Z)-4',4,10-trihydroxy-siamaurone (1) and (E)-4',4,10-trihydroxy-siamaurone (2). The structures of these new compounds were identified by the interpretation of spectroscopic data (mainly 1D and 2D NMR) and by comparison with data reported in the literature. Both of the new compounds were evaluated for their cytotoxicity.
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