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The Effect of Center Volume on In-Hospital Mortality After Aortic and Mitral Valve Surgical Procedures: A
Jeffrey Shuhaiber1, Abby J Isaacs2, Art Sedrakyan2
1Department of Surgery, Swedish American Health System, Rockford, Illinois.
Insights
Higher hospital volume for combined aortic and mitral valve surgery is linked to better patient survival. Centers performing over eight such procedures annually show superior outcomes compared to lower-volume centers.
Area of Science:
- Cardiovascular Surgery
- Health Services Research
- Outcomes Research
Background:
- Assessing the impact of hospital volume on outcomes for complex cardiac procedures.
- Investigating the relationship between center volume and patient mortality in dual valve surgery.
Purpose of the Study:
- To determine the association between hospital volume and the use of dual aortic and mitral valve surgical procedures.
- To evaluate in-hospital outcomes based on annual center volume for multiple-heart valve operations.
Main Methods:
- Utilized the Nationwide Inpatient Sample (NIS) to identify patients undergoing combined aortic and mitral valve repair or replacement.
- Compared patient characteristics and outcomes across low (1-8), medium (9-18), and high (19+) annual volume centers.
- Employed chi-squared tests and adjusted hierarchical logistic regression for statistical analysis.
Main Results:
- Analyzed 87,675 procedures from 1998-2011; high-volume centers treated older patients with CAD and performed more tricuspid valve operations.
- Low-volume centers more frequently used mechanical valves for concomitant aortic and mitral valve replacement (66.1% vs. 45.5%).
- Risk-adjusted in-hospital mortality was significantly lower at medium (OR 0.85) and high-volume (OR 0.66) centers compared to low-volume centers.
Conclusions:
- Hospital volume is a critical determinant of risk-adjusted mortality following combined aortic and mitral valve surgery.
- Centers performing >8 dual valve operations annually demonstrate statistically superior hospital survival.
- Quality improvement initiatives targeting low-volume centers could reduce mortality in valve surgery.
Background:
We aimed to determine the relationship between hospital volume and use of dual aortic and mitral valve surgical procedures.
Methods:
Patients who underwent both aortic and mitral valve repair or replacement during the same hospital stay were identified from the Nationwide Inpatient Sample (NIS). We compared patients' characteristics and in-hospital outcomes by the average annual center volume for multiple-heart valve surgical procedures, grouped into tertiles of patients with low (1 to 8), medium (9 to 18), and high (19+) volume categories using χ(2) tests and adjusted hierarchical logistic regression models.
Results:
From 1998 to 2011 an estimated total of 87,675 patients underwent combined aortic and mitral valve surgical procedures across the United States. Although most patients' characteristics were similar across volume groups, high-volume centers were more likely to treat older patients with coronary artery disease and to perform concomitant tricuspid valve operations. Low-volume centers replaced the aortic and mitral valves concomitantly more frequently with mechanical valves compared with high-volume centers (66.1% vs 45.5%), and this difference persisted across age groups. Compared with low-volume centers, the risk-adjusted odds ratios for in-hospital mortality at medium- and high-volume centers were 0.85 (95% confidence interval [CI]: 0.74 to 0.99) and 0.66 (95% CI: 0.55 to 0.80), respectively. No significant interaction was found between overall facility major cardiac surgery volume and multiple-valve procedure volume with respect to mortality (p = 0.143).
Conclusions:
Hospital volume remains an important factor influencing risk-adjusted mortality after combined aortic and mitral valve surgical procedures. Hospitals that perform more than eight combined aortic and mitral heart valve operations demonstrate a superior statistical hospital survival compared with those that perform less than eight multiple-heart valve operations a year. Further policy interventions aimed to lower hospital mortality in low-volume centers may offer possibilities for quality improvement in the field of valve surgery.
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