Related Experiment Videos
Glutathione monoesters
1Department of Biochemistry, Cornell University Medical College, New York, New York 10021.
Analytical Biochemistry
|November 15, 1989
Abstract:
Glutathione monoesters in which the glycine carboxyl group is esterified are effective cellular glutathione delivery agents because they are readily transported into cells and are deesterified intracellularly. In contrast, glutathione itself is not effectively transported into cells. Detailed procedures are given for the preparation of such esters from glutathione and the corresponding alcohol using hydrogen chloride or sulfuric acid as the catalyst.