Dysfunction of a port-catheter system percutaneously implanted for hepatic arterial infusion chemotherapy due to a fibrin sheath
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Updated: Apr 6, 2026

Percutaneous Hepatic Perfusion PHP with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
Published on: July 31, 2016
Takuji Yamagami1, Tomohiro Matsumoto2, Rika Yoshimatsu2
1Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan. yamagami@koto.kpu-m.ac.jp.
Abstract:
Catheter-related difficulties occurred with a port-catheter system percutaneously implanted by the fixed catheter tip technique for repeated hepatic arterial infusion chemotherapy (HAIC) for unresectable metastatic liver cancer. A side hole in the indwelling catheter opened into the common hepatic artery. Four years and 3 months later, an occluded hepatic artery was diagnosed by arteriography with contrast medium infused via the port. Conversely, celiac arteriography performed from a catheter newly inserted from the femoral artery showed no such occlusion. A new port-catheter system replaced the original one to continue HAIC. Examination revealed a fibrin sheath covering the withdrawn catheter.
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