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Related Experiment Video

Updated: Apr 6, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
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Newborn Glaucoma with Imperforate Pupil.

Anil K Mandal1, Muralidhar Ramappa, Rashmi Krishnamurthy

  • 1*MD Jasti V. Ramanamma Children's Eye Care Centre, L.V. Prasad Eye Institute, Hyderabad, Telangana, India (all authors).

Optometry and Vision Science : Official Publication of the American Academy of Optometry
|July 21, 2015
PubMed
Summary
This summary is machine-generated.

This study presents a novel surgical approach for newborn glaucoma with an imperforate pupil. The combined technique successfully restored corneal clarity and visual function in a pediatric patient.

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Area of Science:

  • Ophthalmology
  • Pediatric Surgery

Background:

  • Congenital glaucoma with an imperforate pupil presents a significant challenge in pediatric eye care.
  • Early surgical intervention is crucial for preserving vision in affected infants.

Observation:

  • A 1-month-old infant diagnosed with left eye congenital glaucoma and an imperforate pupil presented with megalocornea and corneal edema.
  • Intraocular pressure was elevated at 26 mm Hg in the affected eye.
  • Uveal tissue adhered to the posterior corneal surface, obstructing the pupil.

Findings:

  • The surgical procedure involved trabeculectomy, mechanical iris separation from the cornea, and pupillary aperture creation using an automated vitrector.
  • Postoperatively, the corneal edema resolved, and intraocular pressure normalized to 10 mm Hg in both eyes.
  • At 3-year follow-up, the best spectacle-corrected visual acuity was 20/32 in the affected eye, with corneal scarring noted.

Implications:

  • This combined surgical technique appears safe and effective for treating complex newborn glaucoma with pupillary abnormalities.
  • The procedure facilitated restoration of corneal clarity and visual recovery in a pediatric patient.
  • This approach may offer a viable option for similar challenging cases in pediatric ophthalmology.