[Primary non-Hodgkin's lymphoma of the prostate gland]

The clinical, morphological, microscopic, immunohistochemical, and ultrastructural findings in a case of primary non-Hodgkin's malignant lymphoma of the prostate gland is reported. The presenting features were not distinct from those of nodular hyperplasia. Following biopsy, the lesion was classified as monoclonal IgM-secreting, low grade, malignant beta-lymphoma. We discuss the good outcome of this case and the prognostic value of several clinical and morphological parameters. Finally, the therapeutic possibilities for this tumor type are compared with those of extranodal lymphomas in other sites.