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[Normal microflora of the pharyngeal mucosa]
Antibiotiki I Khimioterapiia = Antibiotics and Chemoterapy [Sic]
|October 1, 1989
Summary
Healthy throat microbiomes consist of three distinct microbial groups: indigenous, facultative, and transient. These groups, dominated by Streptococcus and Neisseria, play varied roles in upper respiratory tract health.
Area of Science:
- Microbiology
- Human Microbiome Research
- Upper Respiratory Tract Infections
Background:
- The aerobic microflora of the throat mucosa is crucial for maintaining upper respiratory tract health.
- Understanding the composition and dynamics of this microflora is essential for identifying dysbiosis and potential health risks.
Purpose of the Study:
- To define criteria for estimating microbiocenoses of the upper respiratory tracts in healthy individuals.
- To characterize the different groups of microorganisms colonizing the throat mucosa and their ecological roles.
Main Methods:
- Studied aerobic microflora in 518 healthy individuals aged 1 to 50 years.
- Analyzed colonization frequency, intensity (CFU/ml), species spectrum, and association patterns.
- Investigated the influence of age, season, and urban/rural factors on microbial populations.
Main Results:
- Identified three distinct groups: indigenous (Streptococcus, Neisseria), facultative (Staphylococcus, Corynebacterium, Haemophilus), and transitory (Candida, Escherichia, Klebsiella, etc.).
- Indigenous flora showed stable, intensive colonization, unaffected by external factors.
- Facultative and transitory groups exhibited lower frequency, varied intensity, and were influenced by age, season, and population environment.
Conclusions:
- Established criteria for assessing upper respiratory tract microbiocenoses based on microbial group characteristics.
- Demonstrated the ecological significance of different microbial groups in throat mucosa colonization.
- Highlighted the dynamic nature of facultative and transitory flora, influenced by host and environmental factors.