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Impaired histamine binding by gastric juice of patients with duodenal ulcer
T Zak-Nejmark1, J Małolepszy, J Liebhart
1Department of Internal Diseases, Medical Academy, Wrocław.
Archivum Immunologiae Et Therapiae Experimentalis
|January 1, 1989
Abstract:
Histamine binding by gastric juice from 32 patients with duodenal ulcer and 22 control subjects was tested in vitro. The patients had substantially decreased histamine binding both in basal output as well as in pentagastrin stimulated output. The authors suggest that this phenomenon is involved in etiopathogenesis of chronic ulcer disease.